| 1 | = Updating to Reggie 4.51 = |
| 2 | |
| 3 | == Support for EPICv2 == |
| 4 | |
| 5 | The following changes are required for supporting EPICv2. |
| 6 | |
| 7 | * The `BeadChipType` annotation has changed the `Epic850K` value to `EPICv1` and added `EPICv2`. Existing bead chip items need to be updated with a batch import. |
| 8 | * Use a batch importer to set `BeadChipType=EPICv1` on existing methylation items (assuming to no items are using the EPICv2 chip yet). |
| 9 | * `reggie-config.xml` need to be updated with settings that are specific for each chip type. See [7509] for an example. |
| 10 | * `reggie-config.xml` need to be updated to use the new container: `methylation-beta-v2-minfi1.48.sif` |
| 11 | * Create a new software item for the methylation analysis. |
| 12 | |
| 13 | == Updated WGS variant calling pipeline == |
| 14 | |
| 15 | * `reggie-config.xml` need to be updated to use the new container: `/wgs-variantcall-v2-gatk.4.4.sif` |
| 16 | * Create a new software item for WGS variant calling. |
| 17 | * Existing variant call items should be deleted. |
| 18 | |
| 19 | |