Changes between Initial Version and Version 1 of Ticket #79, comment 9


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Timestamp:
Sep 25, 2013, 1:57:40 PM (11 years ago)
Author:
olle

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  • Ticket #79, comment 9

    initial v1  
    77 3. In order to better check the workings of the normalization procedure, it should be possible to request that extra files with debug information will be stored with the data (default is not to store extra debug information). If chosen, a number of text files named after the java method creating them (after a prefix "`debug`") will be stored in a new directory "`data`". The files will contain values of used parameter values and the fitting values used in the normalization step. When centering over genes, the large number of fitting values are stored in a separate file, "`debugCenterRowsRFitList.txt`" or "`debugCenterRowsForGroupsSeparately.txt`".
    88
     9Notes on the new functionality:
     10
     11 * The default choice in step 1 (option a.) corresponds to the current functionality.
     12 * Even without creation of extra debug files, results of some combinations of assay groups can be easily checked by inspection of the correction factor plots in the overview plots (correction values to be subtracted are shown in blue, and original values in red). If centering over genes where one group contains a single assay, the correction values will totally overlap the original values for that group, leading to a flat line at zero for that assay! Of more practical interest, grouping simultaneous-looking assays together in a group, will lead to normalized values more closely adhering to the zero line for those assays.