= Updating to Reggie 4.26 = == A. Before updating Reggie == === 1. Install a new Picard version on the prime cluster === We need Picard version 2.22.3 or higher since it fixes a problem with !NovaSeq data files and the !CheckIlluminaDirectory function. Verify that the `` setting `reggie-config.xml` is poiting to the correct installation directory and modify if needed. Picard can be downloaded from https://github.com/broadinstitute/picard/releases. == B. Update Reggie == Update Reggie to version 4.26 as usual. Do not forget to run the Installation wizard. == C. After updating Reggie == === 1. Upload CTG sample sheet template === Upload the `CTG_SampleSheet.xlsx` file to the `/home/SCANB/Templates` directory in BASE. === 2. Import variant annotations === In the **RNA library preparation and analysis**/**Variant calling pipeline** section, run the **Import variants for existing variant call raw bioassays** wizard. This wizard will import variants that are found in some interesting genes as annotations to existing raw bioassay items and will take several minutes to run. The same functionality is included in the regular variant calling script so the wizard is not needed in the future. See #1229 for more information.