id,summary,reporter,owner,description,type,status,priority,milestone,component,resolution,keywords,cc 211,Request: R/G quantile normalization,Jari Häkkinen,Martin Svensson,"Copied from the BASE users mailing list (April 27, 2009): Yannick Lippi wrote: > __SECOND QUESTION: R/G quantile normalization > > Jari said: > > Obviously R-G quantile is not supported since the methods in > > net.sf.basedb.normalizers only work on ratios. > > - i am not expert on java developping.. but what does mean: methods in > net.sf.basedb.normalizers only work on ratios Yes, the released normalizers work on ratios for 2-channel data. The normalizers work on 1-channel data also but obviously no on ratios in this case. The same is true for the new normalizers in development (to be relased in 1.1 due soon). > - Do you mean it is not possible to implement plugins to perform R/G > quantile normalizations? Of course, it is possible to implement such plug-ins. However, there is no plan from our side to do that. As always, we are happy to include contributions from other developers. > - how could i pass through this problem? You need to create a plug-in that performs your specific normalization. It should be straightforward to add to the qQuantileNormalizer as options but unfortunately we cannot promise to do this work for you. I'll add R/G qQuantileNormalizations as wish list tickets to the plug-in dev site. Cheers, Jari ",Request,new,major,ZZ A wish list,net.sf.basedb.normalizers,,,